Tesamorelin
A stabilized GHRH analog that preferentially reduces visceral adipose tissue through targeted GH release.
Medically reviewed by Dr. Jonathan Snipes, MD. Last reviewed May 6, 2026.Select your protocol step
Checking your status…A 26-week provider-supervised course, dosed Monday to Friday at night before bed. The first two steps raise the dose and change the vial with it, so the units you draw change too. The final step holds at the top dose and is refilled until the course is done. Your provider reviews and approves every step before the pharmacy fills it.
New to tesamorelin? Start at Weeks 1 to 5. Existing RxPepsDirect patients can also step up from their patient portal once the step below is approved. Pricing is what the pharmacy charges for the medication. Your visit is $39 either way.
What It Is
Tesamorelin is a GHRH analog that has been extensively studied, particularly for its ability to reduce visceral (belly) fat. It's one of the few peptides with significant clinical data.
How It Works
It stimulates the pituitary to release GH, which then targets visceral fat stores. Clinical studies showed significant reduction in trunk fat without affecting subcutaneous fat the same way.
Who It's For
Adults concerned about visceral fat accumulation, metabolic health, and body composition. Particularly effective for those with excess abdominal fat.
Who Should Avoid It
Not for active cancer, pituitary tumors, or pregnancy. Monitor IGF-1 levels.
Protocol & Pricing
OBP Pharmacy Price
$100/15mg
You pay pharmacy price. No markup.
Starting Dose
20 units (0.6mg)
Form
Injectable vial (5mL, 3mg/mL, 15mg total)
Dosing Protocol
20 units subcutaneous injection daily for 5 days, 2 days off. Inject in evening to align with natural GH peak and improve sleep. 20 units = 0.2mL × 3mg/mL = 0.6mg per injection.
Beyond Use Date
90 Days from compounding (USP <797>)
Optimal Balance Pharmacy assigns this date and prints it on your vial label. Always follow the label. Once a multi-dose vial is punctured, the in-use date on the label is shorter than the compounding date shown here.
Already on Tesamorelin? Transfer at your current dose
If another provider prescribes Tesamorelin for you today, you do not have to start the course over at weeks 1 to 5. Select the step that matches your current dose and we will verify it.
How the transfer works
Tesamorelin runs as a 26-week provider-supervised course, and every step above the starting dose is dispensed only after a provider confirms you are already established at the step below it. For a patient transferring in, that proof is your current prescription: pick the step that matches the dose you take today, and upload your documentation during onboarding, after the $39 medical visit. Our provider reviews it and, when it checks out, prescribes the same dose so your treatment continues without interruption.
New to Tesamorelin? Choose Weeks 1 to 5 instead. That is the starting dose, and it needs no documentation.
What you can upload
- A copy of your current prescription (PDF or photo)
- A medical record or chart note from your prescribing provider showing the active medication and dose
- A pharmacy printout or label from your most recent fill
Existing RxPepsDirect tesamorelin patients skip the upload entirely: we match your email to your prior approved visit automatically.
When you'll upload
You'll upload your documentation during onboarding, after you complete the intake form and the contraindication review, just before consent. Your provider sees the document alongside your intake and confirms your step before anything is sent to the pharmacy.
Begin onboarding →Stacking Guide
Stacks Well With
GHRH analog (FDA-approved as Egrifta)
Read the Tesamorelin protocol guide
The only GHRH analog with Phase III trials and an FDA approval. Visceral fat reduction, the 31 percent non-responder rate, and what reaccumulates when you stop.
Related Peptides
Independently tested
Tesamorelin lab test reports
Every Tesamorelin batch dispensed by Optimal Balance Pharmacy is independently tested by Eagle Analytical Services (FDA-registered, A2LA ISO 17025 accredited) for sterility (ScanRDI or Celsis) and bacterial endotoxin (USP <85>). The 2 most recent reports:
| Submission | Lot | Sample | Sterility | Endotoxin | |
|---|---|---|---|---|---|
| ETX-260518-0241 | 051426-13 | TESAMORELIN 3MG/ML 5ML | Pass | Pass <2 EU/mL / 400 EU/mL | Download |
| ETX-260319-0140 | 031826-05 | Tesamorelin 3mg/ml (5ML) TES3 | Pass | Pass <2 EU/mL / 375 EU/mL | Download |
Eagle Analytical Services is an independent FDA-registered laboratory, A2LA accredited to ISO 17025, based in Houston, Texas. They have no commercial relationship with RxPepsDirect. RxPepsDirect prescribes; Optimal Balance Pharmacy compounds and dispenses; Eagle tests every batch. Three separate companies. Browse our full quality program on the quality page.
How to get Tesamorelin prescribed online
Tesamorelin is available by prescription through a licensed telehealth visit and dispensed for human use by a named 503A pharmacy. That is what separates it from research-use-only vials sold without a prescription. There is no subscription and no membership, just a one-time visit fee.
- 1
Complete a $39 medical visit. Answer a short intake about your health history and your goals for Tesamorelin. The $39 fee is the only charge RxPepsDirect collects, paid once, not a recurring subscription.
- 2
A licensed provider reviews it. A US-licensed nurse practitioner or physician reviews your intake and, if Tesamorelin is appropriate for you, writes a patient-specific prescription. The starting dose is typically 20 units (0.6mg).
- 3
The pharmacy compounds and ships it. Optimal Balance Pharmacy, a 503A pharmacy in Texas, compounds Tesamorelin and ships it pre-reconstituted by FedEx overnight in a reusable cooled case. Your fill is Injectable vial (5mL, 3mg/mL, 15mg total), and you pay the pharmacy $100/15mg at wholesale, with no clinic markup, plus a $15 flat FedEx overnight shipping fee charged by the pharmacy.
RxPepsDirect prescribes Tesamorelin in the 29 jurisdictions its medical team is licensed in. Start a $39 visit or browse the full Muscle Growth & Body Composition range. Comparing services first? See how RxPepsDirect stacks up against seven other providers in our best telehealth for compounded peptides comparison.
Common questions about Tesamorelin
- What is tesamorelin?
- Tesamorelin is a 44-amino acid GHRH analog with a longer half-life than sermorelin. It binds GHRH receptors at the pituitary and stimulates endogenous growth hormone release. The molecule is FDA-approved as Egrifta for the reduction of excess abdominal fat in adults with HIV-associated lipodystrophy. It is also used off-label in age-management practices for body composition and visceral fat reduction.
- Is tesamorelin FDA-approved?
- Tesamorelin was FDA-approved as the branded product Egrifta for HIV-associated lipodystrophy. The tesamorelin RxPepsDirect prescribes is not that branded product: Optimal Balance Pharmacy compounds it under Section 503A of the Federal Food, Drug, and Cosmetic Act as a patient-specific prescription, which is legal but is a different regulatory pathway than FDA approval of the specific compounded preparation. Off-label use for visceral adiposity in non-HIV patients is permissible under physician judgment. RxPepsDirect providers prescribe tesamorelin within their state's scope of practice.
- How is tesamorelin dosed at RxPepsDirect?
- The Egrifta-approved dose is 2 mg subcutaneously once daily, and that is the dose behind the published visceral-fat figures. RxPepsDirect titrates in three steps and does not reach it. Step 1 is 20 units from the 3mg/mL vial, which is 0.2mL or 0.6 mg, Monday to Friday. Step 2 moves to the 8mg/mL high-dose vial at 13 units, which is 0.13mL or 1.04 mg, Monday to Friday. Step 3 is the maximum offered and returns to the 3mg/mL vial at 50 units, which is 0.5mL or 1.5 mg, taken daily for 30 days as the final month of the protocol. That ladder runs from about 30 percent of the studied dose to 75 percent of it, so Egrifta trial results describe a higher dose than any step here. Your label and prescriber set which step you are on.
- Where do I inject tesamorelin?
- Subcutaneous injection into the abdomen using a 31-gauge, 5/16-inch (8 mm) needle on a U-100 insulin syringe. Rotate sites within the abdomen with each injection. Most patients dose in the evening before bed; tesamorelin's longer half-life supports once-daily dosing.
- How is tesamorelin supplied?
- Compounded by Optimal Balance Pharmacy under a 503A patient-specific prescription. Ships pre-reconstituted and ready to inject in cold-chain packaging. Every batch is tested by Eagle Analytical Services for sterility and bacterial endotoxin; the Certificate of Analysis is published on this product page. Refrigerate per the printed label.