KPV (in BPC Combos)
Alpha-MSH derived tripeptide that suppresses NF-kB inflammatory pathway for powerful anti-inflammatory immune modulation.
Medically reviewed by Dr. Jonathan Snipes, MD. Last reviewed May 6, 2026.
What It Is
KPV is a tripeptide derived from alpha-MSH with powerful anti-inflammatory properties. Available in our BPC-157 combination vials.
How It Works
It directly suppresses the NF-kB inflammatory pathway, one of the master regulators of inflammation. This provides potent immune modulation without immunosuppression.
Who It's For
Those with inflammatory conditions who are already using BPC-157 stacks. See our BPC-157/TB-500/KPV combo under Recovery & Repair.
Who Should Avoid It
Available via BPC combo formulations. Discuss with provider.
Protocol & Pricing
OBP Pharmacy Price
Via combo
You pay pharmacy price. No markup.
Starting Dose
Per combo
Form
Via combination vial
Dosing Protocol
Per combo formulation. See BPC-157/TB-500/KPV listing.
Beyond Use Date
Inherits BUD of the parent combination vial
Use within this window from the date your vial is compounded. BUD is set per USP <797> sterile compounding standards and printed on every label.
Stacking Guide
Stacks Well With
Three-peptide recovery stack, no copper
Read the KPV (in BPC Combos) protocol guide
The middle rung of the recovery ladder: BPC-157 and TB-500 for repair, KPV for inflammation, and GHK-Cu deliberately left out. Explains the four situations that call for a no-copper vial, and states plainly that no study compares it against the four-peptide version.
Related Peptides
How to get KPV (in BPC Combos) prescribed online
KPV (in BPC Combos) is available by prescription through a licensed telehealth visit and dispensed for human use by a named 503A pharmacy. That is what separates it from research-use-only vials sold without a prescription. There is no subscription and no membership, just a one-time visit fee.
- 1
Complete a $39 medical visit. Answer a short intake about your health history and your goals for KPV (in BPC Combos). The $39 fee is the only charge RxPepsDirect collects, paid once, not a recurring subscription.
- 2
A licensed provider reviews it. A US-licensed nurse practitioner or physician reviews your intake and, if KPV (in BPC Combos) is appropriate for you, writes a patient-specific prescription. The starting dose is typically Per combo.
- 3
The pharmacy compounds and ships it. Optimal Balance Pharmacy, a 503A pharmacy in Texas, compounds KPV (in BPC Combos) and ships it pre-reconstituted by FedEx overnight in a reusable cooled case. Your fill is Via combination vial, and you pay the pharmacy Via combo at wholesale, with no clinic markup, plus a $15 flat FedEx overnight shipping fee charged by the pharmacy.
RxPepsDirect prescribes KPV (in BPC Combos) in the 28 states its medical team is licensed in. Start a $39 visit or browse the full Immune Optimization range.
Common questions about KPV (in BPC Combos)
- What is KPV?
- KPV (lysine-proline-valine) is a tripeptide derived from the C-terminus of alpha-melanocyte-stimulating hormone (alpha-MSH). It is one of the smallest known anti-inflammatory peptides. KPV downregulates NF-kB signaling, reduces pro-inflammatory cytokines (TNF-alpha, IL-6), and is studied for inflammatory bowel disease, chronic gut inflammation, mast cell activation, and skin inflammation.
- What is in the KPV combo formulation?
- The KPV combo is a single subcutaneous injectable that pairs KPV with one or more complementary peptides (BPC-157 for gut healing, GHK-Cu for tissue repair, or both, depending on the protocol). The combo lets one injection address inflammation plus tissue regeneration, common pairing for chronic gut and chronic inflammatory protocols.
- How is KPV dosed?
- Common subcutaneous KPV protocols deliver 200 to 500 mcg per dose once daily. The combo formulation includes complementary peptide doses set by your provider on the protocol sheet. Most protocols run 4 to 8 weeks at a time with breaks. Optimal Balance Pharmacy compounds the combo against RxPepsDirect prescriptions.
- Where do I inject KPV?
- Subcutaneously into the abdomen, upper outer thigh, or back of the upper arm using a 31-gauge, 5/16-inch (8 mm) needle on a U-100 insulin syringe. Sterile syringes are included with every RxPepsDirect shipment. Rotate sites between injections.
- How is the KPV combo supplied?
- Compounded by Optimal Balance Pharmacy under a 503A patient-specific prescription. Ships pre-reconstituted and ready to inject in cold-chain packaging. Every batch is tested by Eagle Analytical Services for sterility and bacterial endotoxin; the Certificate of Analysis is published on this product page.