KPV (in BPC Combos)
Alpha-MSH derived tripeptide that suppresses NF-kB inflammatory pathway for powerful anti-inflammatory immune modulation.
Medically reviewed by Dr. Jonathan Snipes, MD. Last reviewed May 6, 2026.
What It Is
KPV is a tripeptide derived from alpha-MSH with powerful anti-inflammatory properties. Available in our BPC-157 combination vials.
How It Works
It directly suppresses the NF-kB inflammatory pathway, one of the master regulators of inflammation. This provides potent immune modulation without immunosuppression.
Who It's For
Those with inflammatory conditions who are already using BPC-157 stacks. See our BPC-157/TB-500/KPV combo under Recovery & Repair.
Who Should Avoid It
Available via BPC combo formulations. Discuss with provider.
Protocol & Pricing
OBP Pharmacy Price
Via combo
You pay pharmacy price. No markup.
Starting Dose
Per combo
Form
Via combination vial
Dosing Protocol
Per combo formulation. See BPC-157/TB-500/KPV listing.
Beyond Use Date
Inherits BUD of the parent combination vial
Optimal Balance Pharmacy assigns this date and prints it on your vial label. Always follow the label. Once a multi-dose vial is punctured, the in-use date on the label is shorter than the compounding date shown here.
Stacking Guide
Stacks Well With
Alpha-MSH tripeptide (ingredient only)
Read the KPV (in BPC Combos) protocol guide
Three amino acids from the tail of alpha-MSH, carrying part of that hormone's anti-inflammatory activity without its pigment action. The preclinical case is real and gut-focused; the human evidence is nonexistent. Explains why there is no standalone KPV product, and why a fixed-ratio vial means KPV has no dose of its own.
Related Peptides
How to get KPV (in BPC Combos) prescribed online
KPV (in BPC Combos) is available by prescription through a licensed telehealth visit and dispensed for human use by a named 503A pharmacy. That is what separates it from research-use-only vials sold without a prescription. There is no subscription and no membership, just a one-time visit fee.
- 1
Complete a $39 medical visit. Answer a short intake about your health history and your goals for KPV (in BPC Combos). The $39 fee is the only charge RxPepsDirect collects, paid once, not a recurring subscription.
- 2
A licensed provider reviews it. A US-licensed nurse practitioner or physician reviews your intake and, if KPV (in BPC Combos) is appropriate for you, writes a patient-specific prescription. The starting dose is typically Per combo.
- 3
The pharmacy compounds and ships it. Optimal Balance Pharmacy, a 503A pharmacy in Texas, compounds KPV (in BPC Combos) and ships it pre-reconstituted by FedEx overnight in a reusable cooled case. Your fill is Via combination vial, and you pay the pharmacy Via combo at wholesale, with no clinic markup, plus a $15 flat FedEx overnight shipping fee charged by the pharmacy.
RxPepsDirect prescribes KPV (in BPC Combos) in the 29 jurisdictions its medical team is licensed in. Start a $39 visit or browse the full Immune Optimization range. Comparing services first? See how RxPepsDirect stacks up against seven other providers in our best telehealth for compounded peptides comparison.
Common questions about KPV (in BPC Combos)
- What is KPV?
- KPV (lysine-proline-valine) is a tripeptide derived from the C-terminus of alpha-melanocyte-stimulating hormone (alpha-MSH). It is one of the smallest known anti-inflammatory peptides. KPV downregulates NF-kB signaling, reduces pro-inflammatory cytokines (TNF-alpha, IL-6), and is studied for inflammatory bowel disease, chronic gut inflammation, mast cell activation, and skin inflammation.
- Can I order KPV on its own?
- No. RxPepsDirect does not dispense KPV as a standalone vial. It is only available inside the BPC-157/TB-500/KPV combination vial, which pairs KPV with BPC-157 (gut and tissue healing) and TB-500 (systemic recovery) in one fixed-ratio injectable. To get KPV, order the BPC-157/TB-500/KPV combo under Recovery & Repair.
- How is KPV dosed inside the BPC-157/TB-500/KPV combo?
- The combo is dosed as 20 units subcutaneously, Monday through Friday, delivering 0.6mg each of BPC-157, TB-500, and KPV per injection from the 15mg+15mg+15mg vial. All three peptides are dosed together in a fixed ratio; you cannot dose KPV separately from the other two. Your provider sets the exact protocol and course length.
- Where do I inject the BPC-157/TB-500/KPV combo?
- Subcutaneously into the abdomen, upper outer thigh, or back of the upper arm using a 31-gauge, 5/16-inch (8 mm) needle on a U-100 insulin syringe. Sterile syringes are included with every RxPepsDirect shipment. Rotate sites between injections.
- How is the BPC-157/TB-500/KPV combo supplied?
- Compounded by Optimal Balance Pharmacy under a 503A patient-specific prescription. Ships pre-reconstituted and ready to inject in cold-chain packaging. Every batch is tested by Eagle Analytical Services for sterility and bacterial endotoxin; the Certificate of Analysis is published on the BPC-157/TB-500/KPV product page.