Weight Loss & Metabolic

Semaglutide Microdose

A GLP-1 receptor agonist that reduces appetite and slows gastric emptying, delivered at a fraction of the standard weekly dose.

Dr. Jonathan Snipes, MDMedically reviewed by Dr. Jonathan Snipes, MD. Last reviewed May 6, 2026.
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Semaglutide Microdose dispensed by Optimal Balance Pharmacy
Gentle MicrodoseAppetite SupportFewer Side EffectsLonger-Lasting Vial

What It Is

Semaglutide is a GLP-1 receptor agonist, the same class as Ozempic® and Wegovy®. This is the lowest-concentration vial for a gentle microdose of 0.1 to 0.25 mg per week, so the vial lasts longer than standard dosing.

How It Works

It mimics the GLP-1 hormone your body makes after eating, telling your brain you're full and slowing digestion. At microdose levels the effect is milder and slower, which suits people who want to ease in or who are side-effect sensitive.

Who It's For

Adults who want a gentle entry to GLP-1 therapy, are sensitive to side effects, or are microdosing for appetite and metabolic support alongside diet and exercise.

Who Should Avoid It

Not for those with personal/family history of thyroid cancer (MTC), MEN2 syndrome, active pancreatitis, or severe gastroparesis. Not suitable during pregnancy.


Protocol & Pricing

OBP Pharmacy Price

$25/1.2mg

You pay pharmacy price. No markup.

Starting Dose

Prescribed units once weekly (microdose 0.1 to 0.25 mg/week)

Form

Injectable vial (2mL, 0.6mg/mL, 1.2mg total)


Dosing Protocol

Draw the prescribed number of units on a U-100 insulin syringe once weekly. Lowest-concentration vial for a gentle microdose of 0.1 to 0.25 mg per week; the vial lasts longer than standard dosing.

Beyond Use Date

90 Days from compounding (USP <797>)

Use within this window from the date your vial is compounded. BUD is set per USP <797> sterile compounding standards and printed on every label.


Stacking Guide

Do Not Combine With

semaglutide-b12semaglutide-glycinetirzepatide-b12tirzepatide-glycinetirzepatide-microdose

Common questions about Semaglutide Microdose

What is Semaglutide Microdose?
Semaglutide is a GLP-1 receptor agonist, the same class as Ozempic® and Wegovy®. This is the lowest-concentration vial for a gentle microdose of 0.1 to 0.25 mg per week, so the vial lasts longer than standard dosing.
How does Semaglutide Microdose work?
It mimics the GLP-1 hormone your body makes after eating, telling your brain you're full and slowing digestion. At microdose levels the effect is milder and slower, which suits people who want to ease in or who are side-effect sensitive.
Who is Semaglutide Microdose for?
Adults who want a gentle entry to GLP-1 therapy, are sensitive to side effects, or are microdosing for appetite and metabolic support alongside diet and exercise.
How much does Semaglutide Microdose cost?
Semaglutide Microdose costs $25/1.2mg from Optimal Balance Pharmacy at wholesale, with a flat $39 medical visit fee from RxPepsDirect. The form is Injectable vial (2mL, 0.6mg/mL, 1.2mg total).
What is the Beyond Use Date for Semaglutide Microdose?
90 Days from compounding (USP <797>) BUDs are assigned per USP <797> sterile compounding standards and printed on every vial label.