Semaglutide Microdose
A GLP-1 receptor agonist that reduces appetite and slows gastric emptying, delivered at a fraction of the standard weekly dose.
Medically reviewed by Dr. Jonathan Snipes, MD. Last reviewed May 6, 2026.
What It Is
Semaglutide is a GLP-1 receptor agonist, the same class as Ozempic® and Wegovy®. This is the lowest-concentration vial for a gentle microdose of 0.1 to 0.25 mg per week, so the vial lasts longer than standard dosing.
How It Works
It mimics the GLP-1 hormone your body makes after eating, telling your brain you're full and slowing digestion. At microdose levels the effect is milder and slower, which suits people who want to ease in or who are side-effect sensitive.
Who It's For
Adults who want a gentle entry to GLP-1 therapy, are sensitive to side effects, or are microdosing for appetite and metabolic support alongside diet and exercise.
Who Should Avoid It
Not for those with personal/family history of thyroid cancer (MTC), MEN2 syndrome, active pancreatitis, or severe gastroparesis. Not suitable during pregnancy.
Protocol & Pricing
OBP Pharmacy Price
$25/1.2mg
You pay pharmacy price. No markup.
Starting Dose
20 units once weekly (0.12mg microdose; range 0.1 to 0.25 mg/week)
Form
Injectable vial (2mL, 0.6mg/mL, 1.2mg total)
Dosing Protocol
20 units subcutaneous injection once weekly. Titrate up as tolerated per provider. 20 units = 0.2mL × 0.6mg/mL = 0.12mg per injection (gentle microdose; range 0.1 to 0.25mg/week). Hold or step back dose if nausea. Hydration & protein mitigate side effects.
Beyond Use Date
90 Days from compounding (USP <797>)
Use within this window from the date your vial is compounded. BUD is set per USP <797> sterile compounding standards and printed on every label.
Stacking Guide
Do Not Combine With
How to get Semaglutide Microdose prescribed online
Semaglutide Microdose is available by prescription through a licensed telehealth visit and dispensed for human use by a named 503A pharmacy. That is what separates it from research-use-only vials sold without a prescription. There is no subscription and no membership, just a one-time visit fee.
- 1
Complete a $39 medical visit. Answer a short intake about your health history and your goals for Semaglutide Microdose. The $39 fee is the only charge RxPepsDirect collects, paid once, not a recurring subscription.
- 2
A licensed provider reviews it. A US-licensed nurse practitioner or physician reviews your intake and, if Semaglutide Microdose is appropriate for you, writes a patient-specific prescription. The starting dose is typically 20 units once weekly (0.12mg microdose; range 0.1 to 0.25 mg/week).
- 3
The pharmacy compounds and ships it. Optimal Balance Pharmacy, a 503A pharmacy in Texas, compounds Semaglutide Microdose and ships it pre-reconstituted by FedEx overnight in a reusable cooled case. Your fill is Injectable vial (2mL, 0.6mg/mL, 1.2mg total), and you pay the pharmacy $25/1.2mg at wholesale, with no clinic markup, plus a $15 flat FedEx overnight shipping fee charged by the pharmacy.
RxPepsDirect prescribes Semaglutide Microdose in the 28 states its medical team is licensed in. Start a $39 visit or browse the full Weight Loss & Metabolic range.
Common questions about Semaglutide Microdose
- What is Semaglutide Microdose?
- Semaglutide is a GLP-1 receptor agonist, the same class as Ozempic® and Wegovy®. This is the lowest-concentration vial for a gentle microdose of 0.1 to 0.25 mg per week, so the vial lasts longer than standard dosing.
- How does Semaglutide Microdose work?
- It mimics the GLP-1 hormone your body makes after eating, telling your brain you're full and slowing digestion. At microdose levels the effect is milder and slower, which suits people who want to ease in or who are side-effect sensitive.
- Who is Semaglutide Microdose for?
- Adults who want a gentle entry to GLP-1 therapy, are sensitive to side effects, or are microdosing for appetite and metabolic support alongside diet and exercise.
- How much does Semaglutide Microdose cost?
- Semaglutide Microdose costs $25/1.2mg from Optimal Balance Pharmacy at wholesale, with a flat $39 medical visit fee from RxPepsDirect. The form is Injectable vial (2mL, 0.6mg/mL, 1.2mg total).
- What is the Beyond Use Date for Semaglutide Microdose?
- 90 Days from compounding (USP <797>) BUDs are assigned per USP <797> sterile compounding standards and printed on every vial label.