NAD+ Nasal Spray
Intranasal delivery of NAD+ for rapid mucosal absorption and direct CNS access via olfactory pathways.
Medically reviewed by Dr. Jonathan Snipes, MD. Last reviewed May 6, 2026.
What It Is
The same NAD+ in a convenient nasal spray format. Intranasal delivery allows rapid absorption through the nasal mucosa with some direct brain access.
How It Works
Nasal spray delivery provides rapid absorption and some evidence suggests partial transport across the blood-brain barrier via olfactory pathways, potentially enhancing cognitive benefits.
Who It's For
Those who prefer non-injectable administration. People focusing on cognitive benefits of NAD+. Convenient daily maintenance dosing.
Who Should Avoid It
Same as injectable NAD+. Avoid with active cancer or chemotherapy.
Protocol & Pricing
OBP Pharmacy Price
$150/15ml
You pay pharmacy price. No markup.
Starting Dose
10mg/0.1ml
Form
Nasal spray (15mL, 10mg/0.1mL)
Dosing Protocol
1 spray in each nostril daily. 10mg per 0.1mL spray. Alternate nostrils and avoid lying down immediately after dosing.
Beyond Use Date
30 Days from compounding (nasal spray formulation)
Use within this window from the date your vial is compounded. BUD is set per USP <797> sterile compounding standards and printed on every label.
Stacking Guide
Stacks Well With
Longevity coenzyme
Read the NAD+ Nasal Spray protocol guide
Oral supplements have a bioavailability problem the marketing rarely admits. IV produces the flush. Subcutaneous is the at-home middle ground. Not proven to extend lifespan.
Related Peptides
How to get NAD+ Nasal Spray prescribed online
NAD+ Nasal Spray is available by prescription through a licensed telehealth visit and dispensed for human use by a named 503A pharmacy. That is what separates it from research-use-only vials sold without a prescription. There is no subscription and no membership, just a one-time visit fee.
- 1
Complete a $39 medical visit. Answer a short intake about your health history and your goals for NAD+ Nasal Spray. The $39 fee is the only charge RxPepsDirect collects, paid once, not a recurring subscription.
- 2
A licensed provider reviews it. A US-licensed nurse practitioner or physician reviews your intake and, if NAD+ Nasal Spray is appropriate for you, writes a patient-specific prescription. The starting dose is typically 10mg/0.1ml.
- 3
The pharmacy compounds and ships it. Optimal Balance Pharmacy, a 503A pharmacy in Texas, compounds NAD+ Nasal Spray and ships it pre-reconstituted by FedEx overnight in a reusable cooled case. Your fill is Nasal spray (15mL, 10mg/0.1mL), and you pay the pharmacy $150/15ml at wholesale, with no clinic markup, plus a $15 flat FedEx overnight shipping fee charged by the pharmacy.
RxPepsDirect prescribes NAD+ Nasal Spray in the 28 states its medical team is licensed in. Start a $39 visit or browse the full Longevity & Anti-Aging range.
Common questions about NAD+ Nasal Spray
- What is the NAD+ nasal spray?
- The NAD+ nasal spray is a non-injection delivery option compounded by Optimal Balance Pharmacy that delivers nicotinamide adenine dinucleotide intranasally. The active is identical to the injectable formulation; the difference is route only. Nasal absorption is faster than oral but lower-bioavailability than injection.
- Does the nasal NAD+ work as well as the injectable?
- Both routes deliver NAD+ to the systemic circulation but with different pharmacokinetics. Nasal administration produces faster onset (within 5 to 15 minutes for cognitive effects) but lower peak plasma levels. Injection produces a higher peak and longer pharmacokinetic tail. For consistent metabolic and longevity-mechanism support, injection is the more reliable route. The nasal spray is most often used as an acute cognitive-support adjunct or for patients who prefer to avoid injections.
- How do I dose the NAD+ nasal spray?
- Typical protocols deliver 1 to 3 sprays per nostril once or twice daily. Each spray delivers a metered NAD+ dose printed on your shipment protocol sheet. Most patients use the nasal spray in the morning or before cognitive-demand windows.
- Are there side effects with NAD+ nasal spray?
- The most common transient effects are mild nasal irritation at the spray site and a brief flushing or warming sensation in the face. Nasal NAD+ does not produce the chest-pressure or flushing common to fast subcutaneous push of injectable NAD+. Patients with chronic sinus disease should ask their provider whether the nasal route is appropriate.
- How is the NAD+ nasal spray supplied?
- Compounded by Optimal Balance Pharmacy in a metered nasal-spray bottle and ships pre-reconstituted, ready to use. Every batch is tested for identity and the Certificate of Analysis is published on this product page. Refrigerate after first use per the printed label.