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Sermorelin/Ipamorelin

Dual-pathway GH stimulation combining a GHRH analog with a selective ghrelin receptor agonist.

Dr. Jonathan Snipes, MDMedically reviewed by Dr. Jonathan Snipes, MD. Last reviewed May 6, 2026.
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Sermorelin/Ipamorelin dispensed by a licensed U.S. 503A compounding pharmacy

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Synergistic GH ReleaseConvenient ComboLean MuscleRecovery

What It Is

This combination pairs Sermorelin (GHRH analog) with Ipamorelin (ghrelin mimetic) in a single vial for convenience and synergistic GH stimulation.

How It Works

Sermorelin stimulates GHRH receptors while Ipamorelin activates ghrelin receptors. Two different pathways that together produce a stronger, more natural GH pulse.

Who It's For

Those wanting the benefits of both peptides in a single, convenient injection. Great for body composition and recovery goals.

Who Should Avoid It

Same as other GH secretagogues: avoid with active cancer, pituitary tumors.

Ready to add Sermorelin/Ipamorelin?

A licensed provider reviews every order.

Protocol & Pricing

Pharmacy Price

$100

5mL vial of 2 peptides

You pay pharmacy price. No markup.

Starting Dose

20 units (0.6mg/0.72mg)

Form

Injectable vial, 5mL

Your pharmacy label will read

SERMORELIN/ IPAMORELIN

3 MG/ 3.6 MG/ML (5 ML)

The label shows strength per mL, not the total in the vial.

What that means

Each ingredient, in the order the label lists them
IngredientLabel showsIn the vialPer 20 units
Sermorelin3mg/mL15mg0.6mg
Ipamorelin3.6mg/mL18mg0.72mg

Listed in the same order as your label. Multiply each per-mL strength by the 5mL vial to get the amount in the vial. About 25 injections per vial.

Dosing Protocol

20 units subcutaneous injection daily for 5 days, 2 days off. 20 units = 0.2mL × 3mg/mL = 0.6mg Sermorelin + 0.2mL × 3.6mg/mL = 0.72mg Ipamorelin per injection.

Beyond Use Date

90 Days from compounding (USP <797>)

A licensed U.S. 503A compounding pharmacy assigns this date and prints it on your vial label. Always follow the label.

Ready to add Sermorelin/Ipamorelin?

A licensed provider reviews every order.

Stacking Guide

Stacks Well With

BPC-157GHK-Cu

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GHRH analog (GRF 1-29)

Read the Sermorelin/Ipamorelin protocol guide

The only GHRH analog still Category 1 compoundable. Daily injection, 6 to 12 month protocol, 30 to 40 percent non-responder rate, and IGF-1 the biomarker that decides the answer.

Read guide

Related Peptides

BPC-157

A 15-amino acid peptide prescribed as an injection under the skin. Studied for tissue repair, mostly in animals.

$80 · 3mg/mL, 5mL vial (15mg total)

GHK-Cu

A copper peptide that promotes wound healing, collagen synthesis, and tissue remodeling.

$80 · 10mg/mL, 5mL vial (50mg total)

Independently tested

Sermorelin/Ipamorelin certificate of analysis

All 3 Sermorelin/Ipamorelin samples tested for sterility and endotoxin passed both. Latest sample received by the lab Oct 2, 2026.

Every Sermorelin/Ipamorelin batch dispensed by a licensed U.S. 503A compounding pharmacy is independently tested by Eagle Analytical Services (FDA-registered, A2LA ISO 17025 accredited). Sterility testing checks that nothing grows in the sample; the USP <85> endotoxin test checks for bacterial toxins that can cause fever. Below is the lab's own report for each of the 3 most recent lots.

Lot LG342011075, received Oct 2, 2026

Sterility
PassCelsis Sterility Test. Started Oct 2, 2026, completed Oct 12, 2026. Method suitability ETX-251021-0049
Bacterial endotoxin
PassUSP <85>. Measured <2 EU/mL, limit 1750 EU/mL. Started Oct 6, 2026, completed Oct 6, 2026
Sample, as printed
SERMORELIN/ IPAMORELIN 3 MG/ 3.6 MG/ML (5 ML) Injection
Lot #
LG342011075
Storage
Refrigerated
Received by lab
Oct 2, 2026
Laboratory
Eagle Analytical Services Inc., Houston, TX
Submission #
ETX-261002-0323
Signed
Alison Eng, Quality Control Manager
Scan of Eagle Analytical report ETX-261002-0323 for lot LG342011075. Opens the original PDF.
Eagle Analytical report ETX-261002-0323. Open the original PDF (opens in a new tab)

Eagle Analytical Services is an independent FDA-registered laboratory, A2LA accredited to ISO 17025, based in Houston, Texas. They have no commercial relationship with Rx Peps Direct. Rx Peps Direct prescribes; the pharmacy compounds and dispenses; Eagle tests every batch. Three separate companies. Results apply only to the tested sample as received. Browse our full quality program on the quality page.

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How to get Sermorelin/Ipamorelin prescribed online

Sermorelin/Ipamorelin is available by prescription after an online medical review and dispensed for human use by a licensed 503A pharmacy. That is what separates it from research-use-only vials sold without a prescription. There is no membership, just a medical review fee per order, and automatic refills are optional.

  1. 1

    Complete a $39 medical review. Answer a short intake about your health history and your goals for Sermorelin/Ipamorelin. The $39 fee is the only charge Rx Peps Direct collects, paid once, not a recurring subscription.

  2. 2

    A licensed provider reviews it. A US-licensed clinician reviews your intake and, if Sermorelin/Ipamorelin is appropriate for you, writes a patient-specific prescription. The starting dose is typically 20 units (0.6mg/0.72mg).

  3. 3

    The pharmacy compounds and ships it. A licensed 503A compounding pharmacy in Texas compounds Sermorelin/Ipamorelin and ships it pre-reconstituted by FedEx overnight in a reusable cooled case. Your fill is a 5mL injectable vial holding Sermorelin 3mg/mL (15mg total), Ipamorelin 3.6mg/mL (18mg total), and you pay the pharmacy $100 per vial at wholesale, with no clinic markup, plus a $15 flat FedEx overnight shipping fee charged by the pharmacy.

Rx Peps Direct prescribes Sermorelin/Ipamorelin in the 28 states plus Washington, DC where its medical team is licensed. Start your $39 medical review or browse the full Muscle Growth & Body Composition range. Comparing services first? See how Rx Peps Direct stacks up against seven other providers in our best telehealth for compounded peptides comparison.

Ready to add Sermorelin/Ipamorelin?

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Common questions about Sermorelin/Ipamorelin

What is the Sermorelin/Ipamorelin combo?
Sermorelin/Ipamorelin is a compounded blend of two growth hormone secretagogues that work through complementary mechanisms. Sermorelin is a 29-amino acid GHRH analog that increases pituitary GH production. Ipamorelin is a selective ghrelin receptor agonist that triggers a clean GH pulse without raising cortisol or prolactin. Combined, they produce a stronger pulsatile GH release than either peptide alone, similar in concept to the CJC-1295/Ipamorelin pairing but using sermorelin (shorter half-life) rather than CJC-1295 (extended half-life).
Is the combo better than either peptide alone?
Each peptide stimulates a different receptor pathway, so the combined effect is additive rather than redundant. Combined GHRH + ghrelin agonist protocols generally produce stronger IGF-1 elevation than either peptide alone at equivalent doses. Sermorelin/Ipamorelin is often chosen over CJC-1295/Ipamorelin by patients who want a shorter-acting GHRH response that more closely mimics natural pulsatile release.
How is Sermorelin/Ipamorelin dosed?
Common protocols deliver 200 to 500 mcg of each peptide subcutaneously once daily before bed. A licensed U.S. 503A compounding pharmacy compounds the blend against Rx Peps Direct prescriptions; the per-dose draw on your insulin syringe depends on the vial concentration printed on your label. Your provider sets the protocol based on your goals, history, and tolerance.
When and where should I inject the combo?
Inject 30 minutes before bed on an empty stomach. Food (especially carbohydrates) blunts the GH pulse, so most providers recommend nothing to eat for 2 hours before. Subcutaneous injection into the abdomen, upper outer thigh, or back of the upper arm with a 31-gauge insulin syringe. Sterile syringes are included with every Rx Peps Direct shipment.
How is the combo supplied?
Compounded by a licensed U.S. 503A compounding pharmacy under a patient-specific prescription. Ships pre-reconstituted and ready to inject. Every batch is tested by Eagle Analytical Services for sterility (ScanRDI or Celsis) and bacterial endotoxin (USP <85>); the Certificate of Analysis is published on this product page.

Ready to add Sermorelin/Ipamorelin?

A licensed provider reviews every order.