TB-500 is a synthetic fragment of thymosin beta-4, a repair protein the body produces naturally. It binds actin and regulates the cytoskeleton, which is the step that lets repair cells migrate into damaged tissue. It also supports new blood-vessel formation and reduces inflammatory signaling. A licensed U.S. 503A compounding pharmacy compounds it as a 50 mg vial at 10 mg/mL, shipped pre-reconstituted and ready to inject.

How is standalone TB-500 different from the Wolverine Stack?

Same molecule, different packaging. The Wolverine Stack is BPC-157 and TB-500 combined in one vial at a fixed 3 mg/3 mg per mL ratio, so every dose moves both peptides together. The standalone vial lets your provider set the TB-500 dose independently, which matters if you are already running BPC-157 separately or if your provider wants a different balance between local and systemic repair. Do not run the standalone vial at the same time as any combination vial that already contains TB-500.

How do I dose TB-500?

The Rx Peps Direct dose is 25 units (2.5 mg) twice weekly, 3 to 4 days apart (for example Monday and Thursday). The dose stays the same for the whole course, with no step-down. At the 10 mg/mL concentration, 2.5 mg is 25 units (0.25 mL) on a U-100 insulin syringe. The 50 mg vial holds 20 doses, which is 10 weeks on that schedule. Your prescriber sets the length of your course.

Can I combine TB-500 with BPC-157?

Yes, and that is the most common pairing. BPC-157 drives local tissue repair and angiogenesis; TB-500 promotes systemic cell migration. They work on complementary pathways, which is why they are sold together as the Wolverine Stack. Running them as two separate vials gives your provider independent control of each dose. What you should not do is run standalone TB-500 alongside a combination vial that already contains it.

Is TB-500 banned in sport?

Yes. TB-500 is prohibited at all times under WADA category S2. If you compete in a tested sport, tell your provider before starting. This applies to the standalone vial and to every combination vial that contains TB-500.

Who should not take TB-500?

Active malignancy is flagged for provider review, because TB-500 promotes blood-vessel formation. Autoimmune conditions are monitored rather than automatically excluded. Human trial data is limited and most supporting evidence is preclinical, so your provider weighs that in the decision. Rx Peps Direct provides the telehealth prescription; a licensed U.S. 503A compounding pharmacy fills it and ships directly to you.

← Recovery & Repair

TB-500

Name: TB-500
Brand: Rx Peps Direct
SKU: tb-500
Price: 80 USD
Availability: InStock

Synthetic thymosin beta-4 fragment. Binds actin, drives repair-cell migration to injured tissue, and supports new blood-vessel formation.

Medically reviewed by Dr. Jonathan Snipes, MD. Last reviewed May 6, 2026.

Learn the Science ↓

TB-500 dispensed by a licensed U.S. 503A compounding pharmacy

Verify us before you order

Your prescriber
Kim Callender, NP, FNP-BC
Lead prescriber. Medical director: Jonathan Snipes, MD.
Look them up on the federal NPI Registry: Callender, Snipes
TB-500 lab report
Passed sterility and endotoxin
Tested by Eagle Analytical, lot LG342010738, report dated Sep 24, 2026.
Open the report (PDF)
Patient reviews
On Trustpilot
See our reviews on Trustpilot.

Systemic RecoveryCell MigrationAnti-InflammatoryIndependent Dosing

What It Is

TB-500 is a synthetic fragment of thymosin beta-4, a repair protein the body already makes. Until now it was only on our formulary inside the combination vials (Wolverine Stack, BPC-157/TB-500/KPV, KLOW). This is the standalone vial, added when a licensed U.S. 503A compounding pharmacy listed it separately in July 2026.

How It Works

Thymosin beta-4 regulates the actin cytoskeleton, which is what lets repair cells migrate to damaged tissue. It also promotes angiogenesis and dampens inflammatory signaling. The action is systemic rather than local, which is why it complements BPC-157 instead of duplicating it.

Who It's For

Patients with widespread or recurring soft-tissue injuries, patients already running BPC-157 who want to add the systemic half, and cases where the provider wants to dose the two peptides independently rather than at the fixed combination-vial ratio.

Who Should Avoid It

Flag active malignancy for provider review; TB-500 is angiogenic. Monitor autoimmune conditions. Prohibited in tested sport at all times under WADA category S2.

Ready to add TB-500?

A licensed provider reviews every order.

Protocol & Pricing

Pharmacy Price

$80

10mg/mL, 5mL vial (50mg total)

You pay pharmacy price. No markup.

Starting Dose

25 units (2.5mg)

Form

Injectable vial, 5mL

Your pharmacy label will read

TB500

10 MG/ML (5 ML)

The label shows strength per mL, not the total in the vial.

What that means

10mg/mL means 10mg in every mL.
The vial holds 5mL, so 10mg/mL × 5mL = 50mg in the vial.
Each 25-unit injection (0.25mL) gives you 2.5mg, about 20 injections per vial.

Dosing Protocol

25 units subcutaneous injection twice weekly, 3 to 4 days apart (for example Monday and Thursday). 25 units = 0.25mL × 10mg/mL = 2.5mg per injection. The dose stays the same for the whole course, with no step-down.

Beyond Use Date

90 Days from compounding (USP <797>)

A licensed U.S. 503A compounding pharmacy assigns this date and prints it on your vial label. Always follow the label.

Why this dose, and what the evidence shows

From our medical director's protocol for TB-500. Where the evidence is thin, it says so.

Why this dose

The protocol uses two injections each week for a defined treatment period.

This frequency reflects current clinical practice rather than a human dose-ranging study.

No established human pharmacokinetic study defines an optimal TB-500 schedule for tissue recovery.

What the evidence shows

TB-500 is related to thymosin beta-4, a naturally occurring peptide involved in cell migration, tissue repair, and wound-healing pathways.

Animal and laboratory research involving thymosin beta-4 and related compounds provides the biological rationale for interest in TB-500.

Human clinical research has focused primarily on full-length thymosin beta-4 rather than TB-500.

No human clinical trial has established TB-500 as an effective treatment for tendon, muscle, joint, or connective-tissue injury.

For that reason, treatment duration and dosing come from clinical protocols rather than established human therapeutic guidelines.

Each order also carries the $39 prescriber review. Pharmacy prices are the pharmacy's own; we add nothing to them.

Ready to add TB-500?

A licensed provider reviews every order.

Stacking Guide

Stacks Well With

BPC-157GHK-Cu

Do Not Combine With

Wolverine StackBPC-157/TB-500/KPVKLOW

Ready to add TB-500?

A licensed provider reviews every order.

Related Peptides

BPC-157

A 15-amino acid peptide prescribed as an injection under the skin. Studied for tissue repair, mostly in animals.

$80 · 3mg/mL, 5mL vial (15mg total)

GHK-Cu

A copper peptide that promotes wound healing, collagen synthesis, and tissue remodeling.

$80 · 10mg/mL, 5mL vial (50mg total)

Independently tested

TB-500 certificate of analysis

The TB-500 sample tested for sterility and endotoxin passed both. Latest sample received by the lab Sep 21, 2026.

Every TB-500 batch dispensed by a licensed U.S. 503A compounding pharmacy is independently tested by Eagle Analytical Services (FDA-registered, A2LA ISO 17025 accredited). Sterility testing checks that nothing grows in the sample; the USP <85> endotoxin test checks for bacterial toxins that can cause fever. Below is the lab's own report for the most recent lot.

Lot LG342010738, received Sep 21, 2026

Sterility: PassScanRDI Sterility Test. Started Sep 21, 2026, completed Sep 24, 2026. Method suitability ETX-260716-0529
Bacterial endotoxin: PassUSP <85>. Measured <2 EU/mL, limit 1400 EU/mL. Started Sep 22, 2026, completed Sep 22, 2026
Sample, as printed: TB500 10 MG/ML (5 ML) Injection
Lot #: LG342010738
Storage: Refrigerated
Received by lab: Sep 21, 2026
Laboratory: Eagle Analytical Services Inc., Houston, TX
Submission #: ETX-260921-0338
Signed: Alison Eng, Quality Control Manager

Scan of Eagle Analytical report ETX-260921-0338 for lot LG342010738. Opens the original PDF. — Eagle Analytical report ETX-260921-0338. Open the original PDF (opens in a new tab)

Eagle Analytical Services is an independent FDA-registered laboratory, A2LA accredited to ISO 17025, based in Houston, Texas. They have no commercial relationship with Rx Peps Direct. Rx Peps Direct prescribes; the pharmacy compounds and dispenses; Eagle tests every batch. Three separate companies. Results apply only to the tested sample as received. Browse our full quality program on the quality page.

Ready to add TB-500?

A licensed provider reviews every order.

How to get TB-500 prescribed online

TB-500 is available by prescription after an online provider review and dispensed for human use by a licensed 503A pharmacy. That is what separates it from research-use-only vials sold without a prescription. There is no membership, just a medical review fee per order, and automatic refills are optional.

1
Complete a $39 medical review. Answer a short intake about your health history and your goals for TB-500. The $39 fee is the only charge Rx Peps Direct collects, paid once, not a recurring subscription.
2
A licensed provider reviews it. A US-licensed clinician reviews your intake and, if TB-500 is appropriate for you, writes a patient-specific prescription. The starting dose is typically 25 units (2.5mg).
3
The pharmacy compounds and ships it. A licensed 503A compounding pharmacy in Texas compounds TB-500 and ships it pre-reconstituted by FedEx overnight in a reusable cooled case. Your fill is a 5mL injectable vial at 10mg/mL (50mg total), labeled "TB500 10 MG/ML (5 ML)", and you pay the pharmacy $80 per vial at wholesale, with no clinic markup, plus a $15 flat FedEx overnight shipping fee charged by the pharmacy.

Rx Peps Direct prescribes TB-500 in the 28 states plus Washington, DC where its medical team is licensed. Start your $39 provider review or browse the full Recovery & Repair range. Comparing services first? See how Rx Peps Direct stacks up against seven other providers in our best telehealth for compounded peptides comparison.

Ready to add TB-500?

A licensed provider reviews every order.

Common questions about TB-500

What is TB-500?: TB-500 is a synthetic fragment of thymosin beta-4, a repair protein the body produces naturally. It binds actin and regulates the cytoskeleton, which is the step that lets repair cells migrate into damaged tissue. It also supports new blood-vessel formation and reduces inflammatory signaling. A licensed U.S. 503A compounding pharmacy compounds it as a 50 mg vial at 10 mg/mL, shipped pre-reconstituted and ready to inject.
How is standalone TB-500 different from the Wolverine Stack?: Same molecule, different packaging. The Wolverine Stack is BPC-157 and TB-500 combined in one vial at a fixed 3 mg/3 mg per mL ratio, so every dose moves both peptides together. The standalone vial lets your provider set the TB-500 dose independently, which matters if you are already running BPC-157 separately or if your provider wants a different balance between local and systemic repair. Do not run the standalone vial at the same time as any combination vial that already contains TB-500.
How do I dose TB-500?: The Rx Peps Direct dose is 25 units (2.5 mg) twice weekly, 3 to 4 days apart (for example Monday and Thursday). The dose stays the same for the whole course, with no step-down. At the 10 mg/mL concentration, 2.5 mg is 25 units (0.25 mL) on a U-100 insulin syringe. The 50 mg vial holds 20 doses, which is 10 weeks on that schedule. Your prescriber sets the length of your course.
Can I combine TB-500 with BPC-157?: Yes, and that is the most common pairing. BPC-157 drives local tissue repair and angiogenesis; TB-500 promotes systemic cell migration. They work on complementary pathways, which is why they are sold together as the Wolverine Stack. Running them as two separate vials gives your provider independent control of each dose. What you should not do is run standalone TB-500 alongside a combination vial that already contains it.
Is TB-500 banned in sport?: Yes. TB-500 is prohibited at all times under WADA category S2. If you compete in a tested sport, tell your provider before starting. This applies to the standalone vial and to every combination vial that contains TB-500.
Who should not take TB-500?: Active malignancy is flagged for provider review, because TB-500 promotes blood-vessel formation. Autoimmune conditions are monitored rather than automatically excluded. Human trial data is limited and most supporting evidence is preclinical, so your provider weighs that in the decision. Rx Peps Direct provides the telehealth prescription; a licensed U.S. 503A compounding pharmacy fills it and ships directly to you.

Ready to add TB-500?

A licensed provider reviews every order.