GHK-Cu 1% Hair Restoration Solution
GHK-Cu (glycyl-histidyl-lysyl copper) upregulates VEGF expression in dermal papilla cells and modestly inhibits 5-alpha reductase activity, two pathways relevant to follicular regrowth.
Medically reviewed by Dr. Jonathan Snipes, MD. Last reviewed May 6, 2026.
What It Is
A compounded scalp solution containing 1% GHK-Cu (10mg/mL) in a leave-on vehicle. Pickart et al. published the foundational work on GHK-Cu's role in dermal repair; topical formulations show measurable hair density changes over 90 to 180 days in small clinical series. Often layered onto minoxidil or finasteride protocols rather than replacing them.
How It Works
Applied to the scalp once daily, ideally in the evening. The tripeptide-copper complex penetrates the follicle and shifts dermal papilla cell signaling toward the anagen (growth) phase. The aqueous vehicle is designed to leave no residue and be compatible with concurrent minoxidil or finasteride use.
Who It's For
Patients with androgenetic alopecia, telogen effluvium, or general thinning who want a peptide-based adjunct to standard hair-loss treatment. Works for both men and women.
Who Should Avoid It
Known copper allergy. Avoid on broken or inflamed scalp. Discontinue if persistent irritation. Limited topical absorption data in pregnancy or breastfeeding; discuss with provider before use.
Protocol & Pricing
OBP Pharmacy Price
$100/30mL
You pay pharmacy price. No markup.
Starting Dose
1mL applied to scalp once daily
Form
Topical scalp solution (30mL bottle, 10mg/mL GHK-Cu)
Dosing Protocol
Apply 1mL (approximately 20 drops) to clean, dry scalp once daily in the evening. Massage in for 30 seconds. Do not rinse. 30mL bottle covers 30 daily applications. Initial response typically appears at 90 days; full effect at 180 days.
Beyond Use Date
35 Days from compounding (short BUD; use within 5 weeks of fill)
Use within this window from the date your vial is compounded. BUD is set per USP <797> sterile compounding standards and printed on every label.
Stacking Guide
Stacks Well With
Topical copper peptide protocol
Read the GHK-Cu 1% Hair Restoration Solution protocol guide
Why prescription compounded GHK-Cu (1 to 3 percent) outperforms The Ordinary, Biossance, and NIOD (0.05 to 0.1 percent). The seven topical SKUs RxPepsDirect prescribes and how to pick between them.
Related Peptides
Cashmere Cream (GHK-Cu 3% / Niacinamide 4%)
Compounded 3% GHK-Cu and 4% niacinamide daily moisturizer. 30 to 60 times the copper-peptide concentration of OTC serums.
$45/30gmGHK-Cu Biocosmetic Cream (GHK-Cu 3% / Estriol 0.003%)
Compounded 3% GHK-Cu with 0.003% topical estriol. Targeted at mature, post-menopausal, or estrogen-deficient skin.
$100/30gmCommon questions about GHK-Cu 1% Hair Restoration Solution
- What is GHK-Cu 1% Hair Restoration Solution?
- A compounded scalp solution containing 1% GHK-Cu (10mg/mL) in a leave-on vehicle. Pickart et al. published the foundational work on GHK-Cu's role in dermal repair; topical formulations show measurable hair density changes over 90 to 180 days in small clinical series. Often layered onto minoxidil or finasteride protocols rather than replacing them.
- How does GHK-Cu 1% Hair Restoration Solution work?
- Applied to the scalp once daily, ideally in the evening. The tripeptide-copper complex penetrates the follicle and shifts dermal papilla cell signaling toward the anagen (growth) phase. The aqueous vehicle is designed to leave no residue and be compatible with concurrent minoxidil or finasteride use.
- Who is GHK-Cu 1% Hair Restoration Solution for?
- Patients with androgenetic alopecia, telogen effluvium, or general thinning who want a peptide-based adjunct to standard hair-loss treatment. Works for both men and women.
- How much does GHK-Cu 1% Hair Restoration Solution cost?
- GHK-Cu 1% Hair Restoration Solution costs $100/30mL from Optimal Balance Pharmacy at wholesale, with a flat $39 medical visit fee from RxPepsDirect. The form is Topical scalp solution (30mL bottle, 10mg/mL GHK-Cu).
- What is the Beyond Use Date for GHK-Cu 1% Hair Restoration Solution?
- 35 Days from compounding (short BUD; use within 5 weeks of fill) BUDs are assigned per USP <797> sterile compounding standards and printed on every vial label.