5-Amino-1MQ
Inhibits NNMT enzyme to boost NAD+ levels and activate metabolic pathways in fat cells.
Medically reviewed by Dr. Jonathan Snipes, MD. Last reviewed May 6, 2026.What It Is
5-Amino-1MQ is a small molecule that inhibits the NNMT enzyme. By blocking this enzyme, it helps restore metabolic function in fat cells.
How It Works
NNMT is overexpressed in fat tissue and contributes to metabolic slowdown. By inhibiting it, 5-Amino-1MQ helps increase cellular energy production and fat metabolism.
Who It's For
Those experiencing metabolic slowdown or looking to enhance fat metabolism alongside a healthy lifestyle. Often used as part of a comprehensive metabolic optimization stack.
Who Should Avoid It
Limited data on long-term safety. Avoid during pregnancy. Discuss with provider if on metabolic medications.
Protocol & Pricing
OBP Pharmacy Price
$80/25mg
You pay pharmacy price. No markup.
Starting Dose
20 units (1mg)
Form
Injectable vial (5mL, 5mg/mL, 25mg total)
Dosing Protocol
20 units subcutaneous injection daily. 20 units = 0.2mL × 5mg/mL = 1mg per injection. 8–12 weeks duration, may be cycled or extended.
Beyond Use Date
90 Days from compounding (USP <797>)
Use within this window from the date your vial is compounded. BUD is set per USP <797> sterile compounding standards and printed on every label.
Stacking Guide
Stacks Well With
Related Peptides
Independently tested
5-Amino-1MQ lab test reports
Every 5-Amino-1MQ batch dispensed by Optimal Balance Pharmacy is independently tested by Eagle Analytical Services (FDA-registered, A2LA ISO 17025 accredited) for sterility (ScanRDI) and bacterial endotoxin (USP <85>). The most recent report:
| Submission | Lot | Sample | Sterility | Endotoxin | |
|---|---|---|---|---|---|
| ETX-260320-0421 | 032026-03 | 5-AMINO-1MQ 5MG/ML (5ML) | Pass | Pass <2 EU/mL / 250 EU/mL | Download |
Eagle Analytical Services is an independent FDA-registered laboratory, A2LA accredited to ISO 17025, based in Houston, Texas. They have no commercial relationship with PeptideRx. PeptideRx prescribes; Optimal Balance Pharmacy compounds and dispenses; Eagle tests every batch. Three separate companies. Browse our full quality program on the quality page.
Common questions about 5-Amino-1MQ
- What is 5-Amino-1MQ?
- 5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that increases with obesity and aging. NNMT inhibition spares NAD+ and SAM (methyl donor) pools, increases adipocyte energy expenditure, and shifts metabolism toward fat oxidation. The molecule is investigational; most efficacy data is from animal models showing weight loss and improved metabolic markers.
- Does 5-Amino-1MQ work for body composition?
- Animal studies show consistent reductions in white-adipose tissue mass and improvements in metabolic markers when NNMT is inhibited. Human clinical trial data is limited; use is investigational and supervised by the prescribing provider. Patients commonly report mild changes in body composition over 8 to 12 weeks of consistent dosing rather than dramatic short-term effects.
- How is 5-Amino-1MQ dosed?
- Common oral protocols deliver 50 to 150 mg per day, typically dosed once or twice daily with food. Optimal Balance Pharmacy compounds 5-Amino-1MQ in a capsule format against PeptideRx prescriptions; your provider sets the starting dose and titration based on your goals.
- How do I take 5-Amino-1MQ?
- Swallow the capsule whole with water, with or without food. Most protocols dose in the morning or split morning and evening. Avoid dosing within 4 hours of bedtime if you notice the molecule has any subtle activating effect.
- How is 5-Amino-1MQ supplied?
- Dispensed by Optimal Balance Pharmacy in capsule form against PeptideRx prescriptions. Each batch is tested for potency and identity; the Certificate of Analysis is published on this product page. Capsules ship at room temperature and do not require refrigeration.