GHK-Cu Niacinamide Firm Boost Serum
Two-active serum focused on collagen synthesis (GHK-Cu) and barrier repair (niacinamide). Same concentration profile as the SNAP-8 serum minus the SNARE-inhibition peptide; preferred when expression-line targeting is not the goal.
Medically reviewed by Dr. Jonathan Snipes, MD. Last reviewed May 6, 2026.
What It Is
A compounded prescription serum at 3% GHK-Cu and 3% niacinamide in a lightweight aqueous vehicle. Designed for daily firming and barrier support across the face, neck, and decolletage. The 3% GHK-Cu concentration is approximately 30 times higher than mass-market OTC copper peptide serums.
How It Works
Applied to clean face once or twice daily. GHK-Cu signals fibroblast collagen and elastin synthesis; niacinamide reinforces the skin barrier and reduces redness. Layer moisturizer on top.
Who It's For
Patients prioritizing firmness, tone, and barrier integrity over expression-line targeting. Suitable for daily long-term use.
Who Should Avoid It
Known copper allergy. Avoid on broken skin. Patch test if niacinamide-sensitive.
Protocol & Pricing
OBP Pharmacy Price
$120/30mL
You pay pharmacy price. No markup.
Starting Dose
3 to 5 drops applied to face once or twice daily
Form
Topical serum (30mL bottle, GHK-Cu 30mg/mL, Niacinamide 30mg/mL)
Dosing Protocol
Apply 3 to 5 drops to face and neck once or twice daily after cleansing. Layer moisturizer on top. 30mL bottle covers approximately 90 to 120 days of twice-daily use.
Beyond Use Date
180 Days from compounding (USP <797>)
Use within this window from the date your vial is compounded. BUD is set per USP <797> sterile compounding standards and printed on every label.
Stacking Guide
Stacks Well With
Topical copper peptide protocol
Read the GHK-Cu Niacinamide Firm Boost Serum protocol guide
Why prescription compounded GHK-Cu (1 to 3 percent) outperforms The Ordinary, Biossance, and NIOD (0.05 to 0.1 percent). The seven topical SKUs RxPepsDirect prescribes and how to pick between them.
Related Peptides
Cashmere Cream (GHK-Cu 3% / Niacinamide 4%)
Compounded 3% GHK-Cu and 4% niacinamide daily moisturizer. 30 to 60 times the copper-peptide concentration of OTC serums.
$45/30gmGHK-Cu 1% Hair Restoration Solution
Compounded 1% GHK-Cu scalp solution. Tripeptide-copper complex for hair restoration and follicular support.
$100/30mLCommon questions about GHK-Cu Niacinamide Firm Boost Serum
- What is GHK-Cu Niacinamide Firm Boost Serum?
- A compounded prescription serum at 3% GHK-Cu and 3% niacinamide in a lightweight aqueous vehicle. Designed for daily firming and barrier support across the face, neck, and decolletage. The 3% GHK-Cu concentration is approximately 30 times higher than mass-market OTC copper peptide serums.
- How does GHK-Cu Niacinamide Firm Boost Serum work?
- Applied to clean face once or twice daily. GHK-Cu signals fibroblast collagen and elastin synthesis; niacinamide reinforces the skin barrier and reduces redness. Layer moisturizer on top.
- Who is GHK-Cu Niacinamide Firm Boost Serum for?
- Patients prioritizing firmness, tone, and barrier integrity over expression-line targeting. Suitable for daily long-term use.
- How much does GHK-Cu Niacinamide Firm Boost Serum cost?
- GHK-Cu Niacinamide Firm Boost Serum costs $120/30mL from Optimal Balance Pharmacy at wholesale, with a flat $39 medical visit fee from RxPepsDirect. The form is Topical serum (30mL bottle, GHK-Cu 30mg/mL, Niacinamide 30mg/mL).
- What is the Beyond Use Date for GHK-Cu Niacinamide Firm Boost Serum?
- 180 Days from compounding (USP <797>) BUDs are assigned per USP <797> sterile compounding standards and printed on every vial label.