Weight Loss & Metabolic

Tirzepatide Microdose

A dual GIP/GLP-1 receptor agonist that regulates appetite and metabolism, delivered at a fraction of the standard twice-weekly dose.

Dr. Jonathan Snipes, MDMedically reviewed by Dr. Jonathan Snipes, MD. Last reviewed May 6, 2026.
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Tirzepatide Microdose dispensed by Optimal Balance Pharmacy
Gentle MicrodoseDual-Pathway ActionFewer Side EffectsLonger-Lasting Vial

What It Is

Tirzepatide is a dual GIP/GLP-1 receptor agonist, the same class as Mounjaro® and Zepbound®. This is the lowest-concentration vial for a gentle microdose, so the vial lasts longer than standard dosing.

How It Works

By activating both GIP and GLP-1 receptors, tirzepatide supports appetite control and metabolic regulation. At microdose levels the effect is milder and slower, which suits people who want to ease in or who are side-effect sensitive.

Who It's For

Adults who want a gentle entry to dual-pathway GLP-1 therapy, are sensitive to side effects, or are microdosing for appetite and metabolic support alongside diet and exercise.

Who Should Avoid It

Same as semaglutide: avoid with thyroid cancer history, MEN2, pancreatitis, gastroparesis, or pregnancy.


Protocol & Pricing

OBP Pharmacy Price

$45/12mg

You pay pharmacy price. No markup.

Starting Dose

5 units twice weekly (0.3mg/injection, 0.6mg/week microdose)

Form

Injectable vial (2mL, 6mg/mL, 12mg total)


Dosing Protocol

5 units subcutaneous injection twice weekly. Titrate up as tolerated per provider. 5 units = 0.05mL × 6mg/mL = 0.3mg per injection (gentle microdose, 0.6mg/week). Hold or step back dose if nausea. Hydration & protein mitigate side effects.

Beyond Use Date

90 Days from compounding (USP <797>)

Use within this window from the date your vial is compounded. BUD is set per USP <797> sterile compounding standards and printed on every label.


Stacking Guide

Do Not Combine With

tirzepatide-b12tirzepatide-glycinesemaglutide-b12semaglutide-glycinesemaglutide-microdose

How to get Tirzepatide Microdose prescribed online

Tirzepatide Microdose is available by prescription through a licensed telehealth visit and dispensed for human use by a named 503A pharmacy. That is what separates it from research-use-only vials sold without a prescription. There is no subscription and no membership, just a one-time visit fee.

  1. 1

    Complete a $39 medical visit. Answer a short intake about your health history and your goals for Tirzepatide Microdose. The $39 fee is the only charge RxPepsDirect collects, paid once, not a recurring subscription.

  2. 2

    A licensed provider reviews it. A US-licensed nurse practitioner or physician reviews your intake and, if Tirzepatide Microdose is appropriate for you, writes a patient-specific prescription. The starting dose is typically 5 units twice weekly (0.3mg/injection, 0.6mg/week microdose).

  3. 3

    The pharmacy compounds and ships it. Optimal Balance Pharmacy, a 503A pharmacy in Texas, compounds Tirzepatide Microdose and ships it pre-reconstituted by FedEx overnight in a reusable cooled case. Your fill is Injectable vial (2mL, 6mg/mL, 12mg total), and you pay the pharmacy $45/12mg at wholesale, with no clinic markup, plus a $15 flat FedEx overnight shipping fee charged by the pharmacy.

RxPepsDirect prescribes Tirzepatide Microdose in the 28 states its medical team is licensed in. Start a $39 visit or browse the full Weight Loss & Metabolic range.


Common questions about Tirzepatide Microdose

What is Tirzepatide Microdose?
Tirzepatide is a dual GIP/GLP-1 receptor agonist, the same class as Mounjaro® and Zepbound®. This is the lowest-concentration vial for a gentle microdose, so the vial lasts longer than standard dosing.
How does Tirzepatide Microdose work?
By activating both GIP and GLP-1 receptors, tirzepatide supports appetite control and metabolic regulation. At microdose levels the effect is milder and slower, which suits people who want to ease in or who are side-effect sensitive.
Who is Tirzepatide Microdose for?
Adults who want a gentle entry to dual-pathway GLP-1 therapy, are sensitive to side effects, or are microdosing for appetite and metabolic support alongside diet and exercise.
How much does Tirzepatide Microdose cost?
Tirzepatide Microdose costs $45/12mg from Optimal Balance Pharmacy at wholesale, with a flat $39 medical visit fee from RxPepsDirect. The form is Injectable vial (2mL, 6mg/mL, 12mg total).
What is the Beyond Use Date for Tirzepatide Microdose?
90 Days from compounding (USP <797>) BUDs are assigned per USP <797> sterile compounding standards and printed on every vial label.